4-Nitrophenyl α-D-galactopyranoside
CAS No. 7493-95-0
4-Nitrophenyl α-D-galactopyranoside ( PNP-alpha-D-Gal | PNP-α-D-Gal )
产品货号. M27057 CAS No. 7493-95-0
4-硝基苯基 α-D-吡喃半乳糖苷 (PNP-α-D-Gal) 是 4-硝基苯基 (pNP) 吡喃葡萄糖苷的人工底物,用于检测 α-半乳糖苷酶活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | ¥381 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称4-Nitrophenyl α-D-galactopyranoside
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述4-硝基苯基 α-D-吡喃半乳糖苷 (PNP-α-D-Gal) 是 4-硝基苯基 (pNP) 吡喃葡萄糖苷的人工底物,用于检测 α-半乳糖苷酶活性。
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产品描述4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates.(In Vitro):Using 4-nitrophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0. The digestion assays using pNP glycopyranosides as artificial substrates show that yielding liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most.
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体外实验Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most.
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体内实验——
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同义词PNP-alpha-D-Gal | PNP-α-D-Gal
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通路Others
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靶点Other Targets
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受体Alkyl-Chain| Non-cleavable
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研究领域——
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适应症——
化学信息
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CAS Number7493-95-0
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分子量301.25
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分子式C12H15NO8
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 16.67 mg/mL (55.34 mM)
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SMILESO[C@@H]1[C@H](O)[C@@H](O)[C@@H](OC2=CC=C([N+]([O-])=O)C=C2)O[C@@H]1CO
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
产品手册
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